The use of catecholamine at admission for electrical storm in the ICU was associated with an increased 30-day mortality risk (HR 7.95; 95% CI 3.18-19.85).
Cohort (n=253)
No
In patients admitted to the ICU for electrical storm, one-year mortality is high (34%) and primarily driven by heart failure, with catecholamine use at admission strongly predicting 30-day mortality.
Hazard Ratio: 7.95 (95% CI 3.18–19.85)
AIMS: For assessing predictors of early mortality following hospitalization for electrical storm (ES), only limited data are available. The purpose of this study was to assess the incidence and predictors of early mortality following hospitalization in the intensive care unit (ICU) for ES in a large retrospective study. METHODS AND RESULTS: In this retrospective study, we included all patients who were hospitalized for ES from July 2015 to May 2020 in our tertiary centre. A total of 253 patients were included. The median age was 66 56; 73, and 64% had ischemic cardiomyopathy. A total of 37% of patients presented hemodynamic instability requiring catecholamine at admission. A total of 17% of patients presented an acute reversible cause for ES. The one-year mortality was 34% (95% CI, 30-43%), mostly driven by heart failure (HF). The multivariable Cox's regression model identified age, left ventricular ejection fraction, right ventricle dysfunction, haemoglobin level as independent predictors of one-year mortality. The use of catecholamine at admission was identified as the only variable related to the initial management of ES associated with an increased 30-day mortality risk (HR: 7.95 (95%CI, 3.18-19.85). CONCLUSION: In patients admitted for ES in ICU, the one-year mortality remains high and mostly driven by HF. The use of catecholamine at admission is associated with a seven-fold risk for mortality within 30 days. In such patients, the potential use of VT ablation can be questioned and a careful action plan regarding invasive HF-related therapy could be considered.
Ninni et al. (Thu,) conducted a cohort in Electrical storm (n=253). Catecholamine use at admission vs. No catecholamine use at admission was evaluated on 30-day mortality (HR 7.95, 95% CI 3.18-19.85). The use of catecholamine at admission for electrical storm in the ICU was associated with an increased 30-day mortality risk (HR 7.95; 95% CI 3.18-19.85).