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Research Paper | Synapse

February 7, 2022Open Access

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

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Abstract

These findings suggest that EDA possesses potent antidepressant and anxiolytic properties through Sirt1/Nrf2/HO-1/Gpx4 axis and Gpx4-mediated ferroptosis may play a key role in this effect.

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Cite This Study

Dang et al. (Mon,) studied this question.

synapsesocial.com/papers/69df6e54d5404a0bea5931d1 https://doi.org/https://doi.org/10.1186/s12974-022-02400-6

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