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Triazol statt Disulfid: Analoga von Tachyplesin-I (TP-I), in denen beide Disulfidbrücken (in 1) gegen Triazoleinheiten (in 2) ausgetauscht wurden, imitieren die Struktur von TP-I und verfügen über eine ähnliche oder etwas stärkere antibakterielle Aktivität. Optimale Strukturen resultieren, wenn die Cysteinreste in TP-I durch Aminosäuren mit Azid- und Alkinfunktionen ersetzt werden. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Holland‐Nell et al. (Tue,) studied this question.
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