Digitalis Delirium

Article1 December 1950DIGITALIS DELIRIUMJOHN T. KING, F.A.C.P.JOHN T. KING, F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-6-1360 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is hardly necessary to point out the highly practical desirability of understanding as much of the action of digitalis as possible. This drug, of course, is in exceedingly wide use and is loved by many of us "not wisely but too well." It is, as has been pointed out, "not an indifferent drug."1Such effects as anorexia, nausea, vomiting, electrocardiographic changes, slowing of the pulse, bigeminal or trigeminal rhythm, diuresis, color hallucination, amblyopia and scotoma are generally recognized. Occasionally, patients receiving digitalis develop delirium. This is generally, I believe, put down as "cardiac" delirium. However, there has been a...Bibliography1. Duroziez P: De delire et du coma digitaliques, Gaz. hebd. de med. 11: 780, 1874. Google Scholar2. Withering W: An account of the foxglove, etc., 1785, M. Swinney, Birmingham. Google Scholar3. Head H: Certain mental changes that accompany visceral disease, Brain 24: 345, 1901. CrossrefGoogle Scholar4. Hall HO: The hallucinations of digitalis, Am. Med. 1: 598, 1901. Google Scholar5. Hall HO: The delirium and hallucinations of digitalis, Am. Med. 9: 489, 1905. Google Scholar6. Riesman D: Acute psychoses arising during the course of heart disease, Am. J. M. Sc. 161: 157, 1921. CrossrefGoogle Scholar7. Carr J.: Digitalis delirium, M. Clin. North America 9: 1391, 1926. Google Scholar8. Moench GL: Practical therapeutics. Effects of digitalis on the nervous system, M. J. and Rec. 130: 381, 1929. Google Scholar9. Weiss S: Effect of the digitalis bodies on the nervous system, M. Clin. North America 15: 963, 1932. Google Scholar10. Willius FA: Digitalis: its rational use, M. Clin. North America 21: 761, 1937. CrossrefGoogle Scholar11. Smith HL: Cerebral manifestations of digitalis intoxication, Proc. Staff Meet., Mayo Clin. 13: 574, 1938. Google Scholar12. GoodmanGilman LA: The pharmacological basis of therapeutics, 1941, The Macmillan Co., New York. Google Scholar13. Hueper WC: Some toxic aspects of digitalis therapy, New York State J. Med. 45: 1442, 1945. Google Scholar14. BattermanGutner RCLB: Hitherto undescribed neurological manifestations of digitalis toxicity, Am. Heart J. 36: 582, 1948. CrossrefMedlineGoogle Scholar15. BramwellKing CJT: Principles and practice of cardiology, 1942, The Oxford University Press, London, p. 276. Google Scholar16. AndrusPadget ECP: Delirium associated with myocardial insufficiency, Tr. Am. Clin. and Climatol. A. 49: 100, 1933. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Presented to the American Clinical and Climatological Association October 28, 1949. Received for publication April 17, 1950. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNeuropsychiatric Effects of Cardiovascular Drug TherapyRapid reversal of digitalis delirium using digoxin immune fab therapyDigitalis delirium in an elderly womanDigitalis Delirium: Psychiatric ConsiderationsTransient Global Amnesia Associated With Cardiac Arrhythmia and Digitalis IntoxicationDigitalis intoxicationA Comparison of Digitalis Intoxication in Two Separate PeriodsMORTON H. DUBNOW, M.D., HOWARD B. BURCHELL, M.D., PH.D.DIGITALIS INTOXICATION IN ELDERLY PATIENTSDigitalis allergy with nervous system manifestations∗Digitalis DeliriumTOXIC CONFUSIONAL STATESTherapieThe toxic psychoses and allied states 1 December 1950Volume 33, Issue 6Page: 1360-1372KeywordsDeliriumDrugsElectrocardiographyHallucinationsHeart rateNauseaVomiting ePublished: 1 December 2008 Issue Published: 1 December 1950 PDF downloadLoading ...