Role of Mean Platelet Volume (MPV) as a Predictive Marker for Hypertensive Vascular Complications - A Cross-Sectional Study in a Tertiary Care Hospital

BACKGROUND alone or in various combinations has been a major risk factor in and haemorrhagic strokes. The mean platelet volume is a laboratory associated with platelet function and activity. Mean platelet volume is associated with Peripheral Artery Disease (PAD) and uncontrolled. We wanted to study the associated MPV levels in different grades (Grade I and Grade III) of hypertension in comparison with those of healthy. current study was an analytical cross-sectional study, conducted in Velammal College Hospital, Madurai, India, from October 2019 to December 2019. with grade 1 and grade 3 hypertension as cases, and healthy individuals controls were included in the study. Platelet parameters were assessed by the Colter haematology analyser (LH 750) by impendence technology. was used to assess statistical significance. p-value < 0. 05 was considered statistically significant. IBM SPSS version 22 was used for statistical analysis. the study population, 200 (57. 14%) participants were controls, 100 (28. 57%) participants were graded as 1 HT and 50 (14. 29%) participants were as 3 HT. The Mean MPV (fL) among controls was 7. 63 ± 1. 13; it was 8. 04 ± 0. 91 in grade 1 HT group, and it was 10. 05 ± 0. 73 in grade 3 HT group and statistically significant. The mean platelet count (1000 cells /cu. mm) among was 256. 96 ± 62. 78; it was 290. 96 ± 79. 77 in the grade 1 HT group and was 295. 68 ± 60. 55 in grade 3 HT group and was statistically significant. conclude that MPV levels and platelet counts were increased with increasing of hypertension. MPV, as an important indicator of platelet activation can used as a cost-effective diagnostic tool to identify hypertensive patients who at increased risk for thrombotic vascular complications.