Acquired long QT syndrome is highly prevalent in cirrhosis (30% to 70%) and requires careful electrocardiogram monitoring and avoidance of QT-prolonging drugs to mitigate the risk of torsade de pointes.
QT interval prolongation is highly prevalent in cirrhosis and requires careful monitoring and management of risk factors to prevent torsade de pointes.
blockade and altered cytochrome P450 activity), bradycardia, electrolyte abnormalities, underlying cardiomyopathy and acute illness. In patients with cirrhosis, multiple hits and cardiac-hepatic interactions are often required to sufficiently erode the repolarization reserve before long QT syndrome and TdP can occur. While some risk factors are unavoidable, overall risk can be mitigated by electrocardiogram monitoring and avoiding drug interactions and electrolyte and acidbase disturbances. In cirrhotic patients with prolonged QTc interval, a joint effort by cardiologists and hepatologists may be useful and significantly improve the clinical course and outcome.
Lee et al. (Fri,) conducted a review in Cirrhosis with prolonged QT interval. Acquired long QT syndrome is highly prevalent in cirrhosis (30% to 70%) and requires careful electrocardiogram monitoring and avoidance of QT-prolonging drugs to mitigate the risk of torsade de pointes.