Atrial myxoma surgery significantly reduced P-wave duration (108.9 vs 93.0 ms; p<0.001), and post-operative P-wave duration was associated with atrial fibrillation occurrence (HR 0.90; 95% CI 0.83-0.98).
Observational (n=32)
Does atrial myxoma surgery improve atrial electrocardiographic features in patients with atrial myxomas?
Atrial myxoma surgery improves atrial electrocardiographic abnormalities, and post-operative P-wave duration predicts long-term risk of atrial fibrillation.
Absolute Event Rate: 93% vs 108.9%
p-value: p=<.001
INTRODUCTION: Data regarding atrial electrocardiographic parameters in patients with atrial myxomas are scarce. METHODS: We aimed to study atrial electrocardiographic features in patients with atrial myxomas, before and after surgery. We also analyze the incidence of atrial fibrillation during follow-up and its correlation with different P-wave indexes. In total 32 patients in sinus rhythm that underwent atrial myxoma surgery were included. RESULTS: Mean age was 55.0 ± 12.6 years and 18 (56.3%) were women. Ten patients had left atrial enlargement (31.3%). Only one myxoma was located in the right atrium. At baseline seven cases of partial interatrial block (IAB) were detected (21.9%), two in the absence of left atrial enlargement. There were significant differences in atrial electrocardiographic indexes before and after surgery, including P-wave duration (108.9 ± 17.9 ms vs. 93.0 ± 12.4 ms; p < .001), partial IAB (21.9% vs. 3.1%; p = .012) and duration of P-wave terminal force in lead V1 negativity (-0.6 ± 0.3 vs. -0.5 ± 0.3 mm; p = .034). At a mean follow-up of 10.0 ± 5.5 years, 10 patients (31.3%) had experienced at least one episode of atrial fibrillation. Post-operative P-wave duration was associated with atrial fibrillation occurrence during follow-up (Hazard ratio: 0.90, 95% confidence interval: 0.83-0.98; p = .020). CONCLUSIONS: Abnormalities in atrial electrocardiographic indexes are common in atrial myxomas and frequently improve after surgery. Post-operative P-wave duration is associated with atrial fibrillation occurrence during follow-up.
Flores et al. (Thu,) conducted a observational in Atrial myxomas (n=32). Atrial myxoma surgery vs. Pre-surgery baseline was evaluated on P-wave duration (p=<.001). Atrial myxoma surgery significantly reduced P-wave duration (108.9 vs 93.0 ms; p<0.001), and post-operative P-wave duration was associated with atrial fibrillation occurrence (HR 0.90; 95% CI 0.83-0.98).
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