Are higher levels of coagulation factors associated with prevalent and incident atrial fibrillation?
Patients in cross-sectional and longitudinal studies assessing coagulation factors and atrial fibrillation
Higher levels of coagulation factors (exposure)
Lower or normal levels of coagulation factors
Prevalent and incident atrial fibrillationhard clinical
Higher levels of coagulation factors are associated with both prevalent and incident atrial fibrillation, suggesting a prothrombotic state may underlie AF development.
These findings suggest that higher levels of coagulation factors are associated with prevalent and incident AF. These associations are most pronounced with prevalent AF in cross-sectional studies. Limited evidence from longitudinal studies suggests a prothrombotic state underlying AF development.
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Martijn J. Tilly
Electrophysiology
Sven Geurts
Utrecht University
Angelo Maria Pezzullo
Università Cattolica del Sacro Cuore
EP Europace
Erasmus MC
Università Cattolica del Sacro Cuore
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Tilly et al. (Tue,) studied this question.
synapsesocial.com/papers/69d570ea75589c71d767e020 — DOI: https://doi.org/10.1093/europace/euac130