Physiological changes in sex hormones during the regular menstrual cycle have no considerable effect on hemodynamic function and water accumulation in healthy women.
Observational (n=45)
Do physiological variations in sex hormones during the menstrual cycle affect cardiovascular hemodynamics and water content in healthy women?
Physiological changes in sex hormones during the regular menstrual cycle do not have a clinically significant effect on hemodynamic function or water accumulation in healthy women.
Background: Sex hormones influence the cardiovascular (CV) function in women. However, it is uncertain whether their physiological variation related to the regular menstrual cycle affects the CV system. We studied changes in the hemodynamic profile and body’s water content and their relation to sex hormone concentration in healthy women during the menstrual cycle. Material and methods: Forty-five adult women were examined during the early follicular, late follicular, and mid-luteal phases of the same menstrual cycle. The hemodynamic profile was estimated non-invasively by cardiac impedance while water content was estimated by total body impedance. Results were compared with repeated measures ANOVA with post-test, if applicable. Results: There were no significant changes in most hemodynamic and water content parameters between the menstrual cycle phases in healthy women. Left ventricular ejection time differed significantly among phases of the menstrual cycle, with shorter values in the mid-luteal phase (308.4 vs. 313.52 ms, p < 0.05) compared to the late follicular phase. However, the clinical relevance of such small differences is negligible. Conclusions: Changes in sex hormones during the physiological menstrual cycle appear to have no considerable effect on healthy women’s hemodynamic function and water accumulation.
Kwissa et al. (Mon,) conducted a observational in Healthy women of reproductive age (n=45). Menstrual cycle phases (early follicular, late follicular, mid-luteal) vs. Comparisons between phases was evaluated on Hemodynamic profile and body's water content. Physiological changes in sex hormones during the regular menstrual cycle have no considerable effect on hemodynamic function and water accumulation in healthy women.