High systolic blood pressure-related atrial fibrillation/flutter caused 107,091 deaths and 3,337,876 DALYs globally in 2019, with age-standardized rates declining by 5.8% and 7.7% since 1990.
Observational
Yes
The absolute global burden of atrial fibrillation and flutter attributable to high systolic blood pressure has increased substantially over the past three decades, highlighting the need for targeted preventive and therapeutic strategies, particularly in lower sociodemographic index regions.
Atrial fibrillation/atrial flutter (AF/AFL) has progressed to be a public health concern, and high systolic blood pressure (HSBP) remains the leading risk factor for AF/AFL. This study estimated the HSBP attributable AF/AFL burden based on the data from the Global Burden of Disease (GBD) study 2019. Numbers, age-standardized rates (ASR) of deaths, disability-adjusted life years (DALYs), and corresponding estimated annual percentage change (EAPC) were analyzed by age, sex, sociodemographic index (SDI), and locations. Gini coefficient was calculated to evaluate health inequality. Globally, HSBP-related AF/AFL caused 107 091 deaths and 3 337 876 DALYs in 2019, an increase of 142.5% and 105.9% from 1990, respectively. The corresponding mortality and DALYs ASR declined by 5.8% and 7.7%. High-income Asia Pacific experienced the greatest decrease in mortality and DALYs ASR, whereas the largest increase was observed in Andean Latin America. Almost half of the HSBP-related AF/AFL burden was carried by high and high-middle SDI regions, and it was experiencing a shift to lower SDI regions. A negative correlation was detected between EAPC and SDI. Females and elderly people tended to have a higher AF/AFL burden, whereas young adults (30-49 years old) experienced an annual increase in AF/AFL burden. The Gini index of DALYs rate decreased from 0.224 in 1990 to 0.183 in 2019. Despite improved inequality having been observed over the past decades, the HSBP-related AF/AFL burden varied across regions, sexes, and ages. Cost-effective preventive, diagnostic, and therapeutic tools are required to be implemented in less developed regions.
Jin et al. (Mon,) conducted a observational in Atrial fibrillation/atrial flutter. High systolic blood pressure vs. 1990 baseline was evaluated on Deaths and disability-adjusted life years (DALYs). High systolic blood pressure-related atrial fibrillation/flutter caused 107,091 deaths and 3,337,876 DALYs globally in 2019, with age-standardized rates declining by 5.8% and 7.7% since 1990.
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