High-intensity interval training effectively increased brachial artery flow-mediated dilation by 1.59% compared with moderate-intensity continuous training and by 3.80% compared with no exercise.
Meta-Analysis (n=1,437)
Does high-intensity interval training improve vascular function in adults compared to moderate-intensity continuous training or no exercise?
High-intensity interval training is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases, demonstrating superiority over moderate-intensity continuous training.
Effect estimate: WMD 1.59% (95% CI 0.87-2.31)
p-value: p=0.001
Aim: We performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with cardiometabolic diseases. Methods: A search across three electronic databases including Scopus, PubMed, and Web of Science was conducted through February 2022 to identify the randomized trials evaluating HIIT vs. MICT and/or CON on vascular function as measured using brachial artery flow-mediated dilation (FMD) in adults. Separate analyses were conducted for HIIT vs. MICT and/or CON to calculate weighted mean differences (WMD) and 95% confidence intervals (95% CIs) using random or fixed models. Results: = 0.001]. Subgroup analysis showed that HIIT increased FMD in participants with cardiovascular and metabolic diseases, but not in participants who were free of cardiometabolic diseases. In addition, HIIT effectively increased FMD regardless of age and body mass index. Conclusion: We confirm that HIIT is effective for improving vascular function in individuals with metabolic disorders and cardiovascular diseases and has a superior effect compared to MICT, demonstrating time efficiency. Systematic review registration: https://www.crd.york.ac.uk/prospero, identifier CRD42022320863.
Khalafi et al. (Thu,) conducted a meta-analysis in Cardiometabolic diseases and healthy adults (n=1,437). High-intensity interval training (HIIT) vs. Moderate-intensity continuous training (MICT) or no exercise (CON) was evaluated on Change in brachial artery flow-mediated dilation (FMD) compared to MICT (WMD 1.59%, 95% CI 0.87-2.31, p=0.001). High-intensity interval training effectively increased brachial artery flow-mediated dilation by 1.59% compared with moderate-intensity continuous training and by 3.80% compared with no exercise.