Is serum lactate dehydrogenase associated with impaired lung function?
Serum lactate dehydrogenase is negatively correlated with pulmonary function and may serve as a serological monitoring indicator for patients with respiratory diseases.
Serum lactate dehydrogenase was negatively and linearly correlated with pulmonary function indices in the total population analyzed. Based on the total population and different population stratifications, this study determined the threshold values of serum lactate dehydrogenase at the onset of decline of pulmonary function in different populations. This provides a new serological monitoring indicator for patients suffering from respiratory diseases and has implications for patients with possible clinical impairment of pulmonary function. However, our cross-sectional study was not able to determine a causal relationship between these two factors, and further research is needed.
Hu et al. (Thu,) studied this question.