In patients at risk of heart failure, augmentation index measured immediately after exercise was significantly inversely associated with exercise tolerance (β=-0.342, P=0.003).
Cross-Sectional (n=106)
No
Does exercise-induced change in aortic stiffness correlate with exercise tolerance in patients at risk of heart failure?
Effect estimate: β=-0.342
p-value: p=0.003
BACKGROUND: The number of patients with heart failure (HF) has increased, and it is crucial to prevent the development of HF in patients at risk of HF. The present study aimed to risk stratify patients in Stage A and B HF based on associations between exercise-induced changes in aortic stiffness and exercise tolerance. METHODS AND RESULTS: peak subgroups using a cut-off value of 60%, RM decreased immediately after exercise and remained lower 5 min after exercise in the group with preserved exercise tolerance, but recovered to baseline levels 5 min after exercise in the group with reduced exercise tolerance. CONCLUSIONS: Exercise-induced increases in aortic stiffness were associated with exercise tolerance in patients at risk of HF, suggesting that exercise-induced changes in aortic stiffness may be useful to stratify high-risk patients.
Mizoguchi et al. (Mon,) conducted a cross-sectional in Stage A and B Heart Failure (n=106). Aortic stiffness (Augmentation index and Reflection magnitude) vs. Preserved exercise tolerance (%VO2peak ≥60%) was evaluated on Association between augmentation index (AIx) immediately after exercise and percentage of predicted peak oxygen consumption (%VO2peak) (β=-0.342, p=0.003). In patients at risk of heart failure, augmentation index measured immediately after exercise was significantly inversely associated with exercise tolerance (β=-0.342, P=0.003).