Two patients experienced severe structural valve deterioration due to leaflet disruption 23 and 54 months after TAVR with the ACURATE Neo valve, requiring surgical explantation and replacement.
Case Report (n=2)
No
Highlights the rare but severe complication of leaflet disruption leading to structural valve deterioration in the self-expanding ACURATE Neo TAVR prosthesis, which was managed with surgical replacement.
Structural valve deterioration (SVD) of transcatheter implanted aortic valve (TAVR) prostheses leading to prosthesis dysfunction is an uncommon yet increasingly described complication. Literature is scarce on specific mechanisms and clinical presentation of SVD after TAVR, notably on self-expanding valve ACURATE Neo. We report on two cases with severe bioprosthetic failure after ACURATE Neo implantation due to leaflet disruption, and we treated them with surgical aortic valve replacement. Based on the literature, we further discuss the incidence of SVD after TAVR, the durability of ACURATE NEO, and the modes of failure of biological valve prostheses.
Schaeffer et al. (Thu,) conducted a case report in Severe structural valve deterioration after TAVR (n=2). ACURATE Neo TAVR was evaluated on Structural valve deterioration (SVD) leading to bioprosthetic failure. Two patients experienced severe structural valve deterioration due to leaflet disruption 23 and 54 months after TAVR with the ACURATE Neo valve, requiring surgical explantation and replacement.
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