Pericardial fat volume was significantly associated with cardiovascular diseases (95% CI 1.05-1.27).
Meta-Analysis
Is pericardial fat volume associated with cardiovascular diseases?
Pericardial fat volume is significantly associated with cardiovascular diseases, suggesting it may be a useful addition to established cardiovascular risk scores.
OBJECTIVE: Previous studies investigated the effect of pericardial fat on cardiovascular diseases. However, until now there was no systematic review and meta-analysis investigated this association, thus we conducted this article to assess the relationship between pericardial fat and cardiovascular diseases. METHODS: We searched PubMed, The Cochrane Library, Scopus, Google Scholar and Clinicaltrials.gov to select observational studies reported the relationship between pericardial fat and cardiovascular diseases including coronary artery disease (CAD), ventricular dysfunction, heart failure (HF), atrial fibrillation (AF), major adverse cardiac events (MACE), coronary artery calcifications (CAC), arrhythmias other than atrial fibrillation, and cardiovascular events prediction scores. Meta XL 5.3 was used for data analysis. RESULTS: ; 95% CI: 1.05-1.27). On the other hand, there was no enough data about the relationship between pericardial fat with arrhythmias other than atrial fibrillation or cardiovascular risk scores. CONCLUSION: The analysis demonstrated that the relationship between pericardial fat volume and cardiovascular diseases was significant. Since pericardial fat is a good predictor of obesity, it suggests investigating its relationship and adds on effect to previously established risk factor to evaluate the possibility of incorporating it with cardiovascular risk scores.
Al-Makhamreh et al. (Thu,) conducted a meta-analysis in Cardiovascular diseases. Pericardial fat was evaluated on Cardiovascular diseases (95% CI 1.05-1.27). Pericardial fat volume was significantly associated with cardiovascular diseases (95% CI 1.05-1.27).