Does baseline more-than-mild aortic regurgitation predict better left ventricular mass index regression at one year after TAVR?
Concomitant more-than-mild aortic regurgitation at baseline predicts better left ventricular reverse remodeling (LVMi regression) one year after TAVR.
Abstract Background We aim to determine predictors of inadequate left ventricular mass index (LVMi) regression at mid-term after transcatheter aortic valve replacement (TAVR), including the potential role of epicardial adipose tissue (EAT). Methods We retrospectively reviewed patients with both echocardiographic assessments and multi-slice computed tomography (MSCT) obtained one year after TAVR. The change of LVMi, the volume and the average CT attenuation of EAT from baseline to one-year follow-up was calculated. Patients were divided into two groups by the percentage change of LVMi at a cut-off of 15%. Results A total of 152 patients were included with a median age of 74 years (interquartile range IQR 69–78 years) and 56.6% being male. LVMi decreased (P mild (P = 0.001) and the change in the average CT attenuation of EAT (P = 0.026) were different between the decrease of LVMi ≥ 15% and mild at baseline was the only statistically significant predictor of a decrease of LVMi < 15% at one year (OR 0.33, 95% CI: 0.13 to 0.84, P = 0.021) in multivariate regression. Conclusions Concomitant more-than-mild AR might predict better left ventricular reverse remodeling regression after TAVR.
Yang et al. (Mon,) studied this question.