The total number of segments with motion abnormalities independently predicted large myocardial infarct size (>19%) (OR 1.976; 95% CI 1.539-2.538; P<0.0001), outperforming global longitudinal strain.
Observational (n=380)
Does the number of segments with motion abnormalities on speckle-tracking echocardiography better predict large myocardial infarct size compared to global longitudinal strain and global work efficiency in patients with STEMI?
The total number of segments with motion abnormalities on speckle-tracking echocardiography provides superior prognostic value for predicting large myocardial infarct size compared to established parameters like global longitudinal strain.
Odds Ratio: 1.976 (95% CI 1.539–2.538)
p-value: p=<0.0001
BACKGROUND: The relationship between the number of segments with motion abnormalities (SMA) on the bull's-eye plots of speckle-tracking echocardiography (STE) and myocardial infarct size (MIS) on late gadolinium-enhanced cardiac MRI (LGE-cMRI) has not been well characterized. This study aimed to determine MIS using the number of SMA in patients with acute myocardial infarction (MI). METHODS: Left ventricular two-dimensional STE and LGE-cMRI were performed in 380 patients with ST-segment elevation MI within 48 h and 5-6 days after primary percutaneous intervention, respectively. RESULTS: Patients with impaired global and regional myocardial strain, work and greater number of SMA had significantly larger infarcts ( P 19%). The area under receiver operating characteristic curve (AUC) of 0.904 (0.866~0.942) for total number of SMA was superior to that for global longitudinal strain (GLS, AUC = 0.813, 0.761~0.865), global work efficiency (GWE, AUC = 0.794, 0.730~0.857) and number of SPSM (AUC = 0.851, 0.804-0.899) to predict a large MIS ( P < 0.05). The optimal cutoff value of total number of SMA was 7, with a sensitivity of 85.31%, a specificity of 81.48%, and an accuracy of 83.27%. CONCLUSION: Total number of SMA is better associated with infarct size, which provided an incremental prognostic value above established prognostic parameters such as GLS and GWE.
Yu et al. (Wed,) conducted a observational in ST-segment elevation MI (n=380). Number of segments with motion abnormalities (SMA) was evaluated on Large myocardial infarct size (>19%) (OR 1.976, 95% CI 1.539-2.538, p=<0.0001). The total number of segments with motion abnormalities independently predicted large myocardial infarct size (>19%) (OR 1.976; 95% CI 1.539-2.538; P<0.0001), outperforming global longitudinal strain.