Does PCI reduce cardiovascular death, myocardial infarction, or MACE compared to optimal medical therapy in patients with a single remaining coronary CTO?
In patients with a single coronary CTO, PCI is safe and reduces MACE (driven by less ischaemia-driven revascularization) compared to optimal medical therapy at 3 years, though it does not reduce cardiovascular death or myocardial infarction.
At 3 years there was no difference in the rate of cardiovascular death or myocardial infarction between PCI or OMT among patients with a remaining single coronary CTO. The MACE rate was higher in the OMT group due largely to ischaemia-driven revascularisation. CTO PCI appears to be a safe option for patients with a single remaining significant coronary CTO. CinicalTrials.gov: NCT01760083.
Werner et al. (Fri,) studied this question.
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