Transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot can render ventricular tachycardia inaccessible to catheter ablation due to progressive degenerative remodelling.
Does electrophysiology testing before transcatheter pulmonary valve replacement improve management of ventricular tachycardia in patients with repaired tetralogy of Fallot?
Electrophysiology testing before transcatheter pulmonary valve replacement in repaired tetralogy of Fallot is highlighted as important because the valve replacement can render ventricular tachycardia inaccessible to subsequent catheter ablation.
Graphical AbstractOpen in new tabDownload slidePathophysiology of ventricular arrhythmia for repaired tetralogy of Fallot in relation to native right ventricular outflow tract transcatheter pulmonary valve replacement. Following repair, progressive degenerative remodelling incurs a risk for sustained monomorphic ventricular tachycardia. With transcatheter pulmonary valve replacement, ventricular tachycardia can become inaccessible to catheter ablation. A and B, trichrome stain demonstrating interstitial and replacement fibrosis in regions between the pulmonary annulus and ventriculotomy incision or ventricular septal defect patch, respectively (courtesy of UCLA pathology archives).
Moore et al. (Tue,) conducted a other in Repaired tetralogy of Fallot. Electrophysiology testing before transcatheter pulmonary valve replacement was evaluated. Transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot can render ventricular tachycardia inaccessible to catheter ablation due to progressive degenerative remodelling.