What are the consensus recommendations for the diagnosis and practical management of digoxin toxicity?
This consensus document provides practical recommendations for the diagnosis and management of digoxin toxicity, addressing a gap in current clinical guidelines.
There are currently no universally accepted guidelines for the management of digoxin toxicity. In the absence of clinical practice guidelines, a set of consensus recommendations for management of digoxin toxicity in the clinical setting were developed through a modified Delphi approach. The recommendations highlight the importance of early recognition of signs of potentially life-threatening toxicity that requires immediate treatment with digoxin-specific antibodies. The consensus identifies a straightforward approach to dosing immune antibody fragments according to the presence or absence of signs of life-threatening toxicity. Supportive measures and management of specific signs of toxicity are also covered.
Andrews et al. (Fri,) studied this question.