Healthy postmenopausal females exhibit reduced respiratory modulation of sympathetic nerve activity compared to premenopausal females, which is negatively related to resting blood pressure.
Observational
Is respiratory modulation of sympathetic nerve activity altered in healthy postmenopausal females compared to premenopausal females?
Reduced respiratory sympathetic modulation in postmenopausal females may contribute to age-related sympathetic activation and higher resting blood pressure.
The current study demonstrates that respiratory modulation of sympathetic nerve activity (SNA) is reduced in healthy postmenopausal (PMF) versus premenopausal females (YF). Furthermore, respiratory sympathetic modulation was negatively related to resting blood pressure in postmenopausal females, such that blood pressure was greater in individual with less modulation. Reduced respiratory sympathetic modulation may have implications for the autonomic control of blood pressure in aging postmenopausal females, by contributing to age-related sympathetic activation and reducing acute, respiratory-linked blood pressure variation.
Adams et al. (Fri,) conducted a observational in Healthy postmenopausal and premenopausal females. Postmenopausal status vs. Premenopausal status was evaluated on Respiratory modulation of sympathetic nerve activity (SNA). Healthy postmenopausal females exhibit reduced respiratory modulation of sympathetic nerve activity compared to premenopausal females, which is negatively related to resting blood pressure.