Does a single-pill combination of perindopril/indapamide/amlodipine improve adherence, clinical outcomes, and healthcare costs compared to a multiple-pill combination?
Using a single-pill combination for antihypertensive therapy improves medication adherence and reduces both cardiovascular events and healthcare costs compared to multiple-pill regimens.
The SPC of PER/IND/AML, compared with multiple-pill combination, is associated with higher adherence to medication, lower incidence of CV events and mortality, and reduced healthcare costs.
Snyman et al. (Tue,) studied this question.