A non-invasive near-field RF sensor accurately extracted systolic time intervals in a pig model across systemic pressures, with mean relative errors of -4.4 ms for ICT and -3.6 ms for LVET.
Does a non-invasive near-field RF sensor accurately extract systolic time intervals compared to phonocardiogram and aortic catheterization in a pig model under varying blood pressures?
A non-invasive near-field RF sensor can accurately extract systolic time intervals with less than 5 ms relative error across different blood pressure states in a pig model.
Screening and monitoring for cardiovascular diseases (CVDs) can be enabled by analyzing systolic time intervals (STIs). As CVDs have a strong causal correlation with hypertension, it is important to validate STI sensor accuracy in hypertensive hearts to ensure consistent performance in this prevalent cardiac disease state. This work presents STI extraction using a non-invasive near-field radio-frequency (RF) sensor during normotension, hypertension, and hypotension in a pig model. Waveform features of semilunar and atrioventricular valve dynamics during systole were extracted to derive isovolumic contraction time (ICT) and left ventricular ejection time (LVET), benchmarked by a phonocardiogram and aortic catheterization. Study-wide mean relative ICT and LVET errors were -4.4ms and -3.6ms, respectively, demonstrating high accuracy during both normal and abnormal systemic pressures.Clinical relevance- This work demonstrates accurate STI extraction with relative error less than 5 ms from a non-invasive near-field RF sensor during normotensive, hypotensive, and hypertensive systemic pressures, validating the sensor's accuracy as a screening tool during this disease state.
Conroy et al. (Mon,) conducted a other in Hypertension and hypotension (pig model). Non-invasive near-field radio-frequency (RF) sensor vs. Phonocardiogram and aortic catheterization was evaluated on Isovolumic contraction time (ICT) and left ventricular ejection time (LVET) relative errors. A non-invasive near-field RF sensor accurately extracted systolic time intervals in a pig model across systemic pressures, with mean relative errors of -4.4 ms for ICT and -3.6 ms for LVET.
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