Cardiovascular preparticipation screening in children aged 8-15 years identified at-risk cardiovascular diseases more frequently in those ≥12 years (0.06%/evaluation) than <12 years (0.02%, p=0.02).
Observational (n=25,251)
Yes
What is the incidence of sudden cardiac arrest and death and the diagnostic yield of cardiovascular preparticipation screening in children aged 8-15 years?
The incidence of sudden cardiac arrest/death and the diagnostic yield of preparticipation screening are substantially higher in children aged ≥12 years compared to those <12 years, suggesting screening may be more useful beyond age 12.
Absolute Event Rate: 0.06% vs 0.02%
p-value: p=0.02
OBJECTIVE: Evidence on the increased risk of sports-related sudden cardiac arrest and death (SCA/D) and the potential benefit of cardiovascular preparticipation screening (PPS) in children is limited. We assessed the burden and circumstances of SCA/D and the diagnostic yield of cardiovascular PPS in children aged 8-15 years. METHODS: Data on the incidence and causes of SCA/D from 2011 to 2020 were obtained from the Veneto region (Italy) sudden death registry, hospital records and local press. During the same period, we assessed the results of annual PPS in 25 251 young competitive athletes aged 8-15 years who underwent 58 185 evaluations (mean 2.3/athlete) in Padua, Italy. RESULTS: Over 10 years, 26 SCA/D occurred in children aged 8-15 years in the Veneto region: 6 in athletes (incidence 0.7/100 000/year, all ≥12 years) versus 20 in non-athletes (0.7/100 000/year, 17/20 ≥12 years). In total, 4/6 athletes versus 1/20 non-athletes survived. The cause of SCA/D remained unexplained in four athletes and in nine non-athletes. No athlete suffered SCA/D from structural diseases potentially identifiable by PPS. The incidence of SCA/D in athletes and non-athletes was 0.2/100 000/year in the 8-11 years group versus 1.3/100 000/year in the 12-15 years group. PPS identified 26 new diagnoses of cardiovascular diseases (CVDs) at risk of SCA/D, more often in children ≥12 years old (0.06%/evaluation) than <12 years old (0.02%/evaluation, p=0.02). Among athletes with a negative PPS, two suffered unexplained SCA/D during follow-up, one during exercise. CONCLUSIONS: In children aged 8-15 years, the incidence of SCA/D and the yield of PPS for identifying at-risk CVD were both substantially higher in those ≥12 years, suggesting that systematic PPS may be more useful beyond this age.
Graziano et al. (Wed,) conducted a observational in Sudden cardiac arrest and death (SCA/D) (n=25,251). Cardiovascular preparticipation screening (PPS) vs. Children <12 years old was evaluated on Diagnostic yield of cardiovascular diseases at risk of SCA/D per evaluation (p=0.02). Cardiovascular preparticipation screening in children aged 8-15 years identified at-risk cardiovascular diseases more frequently in those ≥12 years (0.06%/evaluation) than <12 years (0.02%, p=0.02).
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