Does exposure to hypotension during an ICU stay increase the risk of mortality and acute kidney injury?
Hypotension during an ICU stay is associated with a severity-dependent increase in mortality.
Exposure to hypotension during ICU stay was associated with increased mortality and AKI in the majority of included studies, and associations for both outcomes increased with increasing hypotension severity. The meta-analysis reinforced the descriptive findings regarding mortality but did not yield similar support for AKI.
Schuurmans et al. (Mon,) studied this question.