High-risk sleep patterns, characterized by snoring, daytime sleepiness, abnormal sleep duration, and inappropriate bedtime, were associated with a significantly increased risk of cardiovascular disease (OR 47.73).
Cross-Sectional (n=6,830)
Do high-risk sleep characteristics increase the risk of cardiovascular disease in adults over 40 years of age?
Adverse sleep characteristics, particularly when combined into high-risk sleep patterns, are strongly associated with increased cardiovascular disease risk, especially in patients with hypertension and diabetes.
Odds Ratio: 47.73 (95% CI 36.73–62.04)
p-value: p=<0.01
Background: The relationship between sleep characteristics and cardiovascular disease (CVD) risk has yet to reach a consistent conclusion, and more research needs to be carried out. This study aimed to explore the relationship between snoring, daytime sleepiness, bedtime, sleep duration, and high-risk sleep patterns with CVD risk. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) 2015-2018 were collected and analyzed. Multivariable logistic regression was used to evaluate the relationship between snoring, daytime sleepiness, bedtime, sleep duration, high-risk sleep patterns, and CVD risk. Stratified analysis and interaction tests were carried out according to hypertension, diabetes and age. Results: The final analysis contained 6,830 participants, including 1,001 with CVD. Multivariable logistic regression suggested that the relationship between snoring OR = 7.37,95%CI = (6.06,8.96), daytime sleepiness OR = 11.21,95%CI = (9.60,13.08), sleep duration shorter than 7 h OR = 9.50,95%CI = (7.65,11.79) or longer than 8 h OR = 6.61,95%CI = (5.33,8.19), bedtime after 0:00 OR = 13.20,95%CI = (9.78,17.80) compared to 22:00-22:59, high-risk sleep patterns OR = 47.73,95%CI = (36.73,62.04) and CVD risk were statistically significant. Hypertension and diabetes interacted with high-risk sleep patterns, but age did not. Conclusions: Snoring, daytime sleepiness, excessive or short sleep duration, inappropriate bedtime, and high-risk sleep patterns composed of these factors are associated with the CVD risk. High-risk sleep patterns have a more significant impact on patients with hypertension and diabetes.
Hou et al. (Wed,) conducted a cross-sectional in Cardiovascular disease (n=6,830). High-risk sleep patterns vs. Medium-low-risk sleep patterns was evaluated on Cardiovascular disease risk (OR 47.73, 95% CI 36.73-62.04, p=<0.01). High-risk sleep patterns, characterized by snoring, daytime sleepiness, abnormal sleep duration, and inappropriate bedtime, were associated with a significantly increased risk of cardiovascular disease (OR 47.73).