FIGURE 4 from Stromal Signals Dominate Gene Expression Signature Scores That Aim to Describe Cancer Cell–intrinsic Stemness or Mesenchymality Characteristics

Comparison of EMT-related signature scores in eight scRNA-seq datasets. The dot plot shows the module scores of EMT-related signatures and the number of cells expressing them in the different cell types. Each panel displays dot plots to quantify the expression of individual signatures in four different tissues (malignant, endothelial, myofibroblast, and fibroblast) derived from scRNA-seq datasets for BRCA, colorectal cancer (CRC), glioma, and HNSC. X, Unavailable cell type.