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Abstract Artificial intelligence has made substantial progress in many medical application scenarios. The quantity and complexity of pathology images are enormous, but conventional visual screening techniques are labor-intensive, time-consuming, and subject to some degree of subjectivity. Complex pathological data can be converted into mineable image features using artificial intelligence image analysis technology, enabling medical professionals to quickly and quantitatively identify regions of interest and extract information about cellular tissue. In this study, we designed a medical information assistance system for segmenting pathology images and quantifying statistical results, including data enhancement, cell nucleus segmentation, model tumor, and quantitative analysis. In cell nucleus segmentation, to address the problem of uneven healthcare resources, we designed a high-precision teacher model (HRMEDT) and a lightweight student model (HRMEDS). The HRMEDT model is based on visual Transformer and high-resolution representation learning. It achieves accurate segmentation by parallel low-resolution convolution and high-scaled image iterative fusion, while also maintaining the high-resolution representation. The HRMEDS model is based on the Channel-wise Knowledge Distillation approach to simplify the structure, achieve faster convergence, and refine the segmentation results by using conditional random fields instead of fully connected structures. The experimental results show that our system has better performance than other methods. The Intersection over the Union (IoU) of HRMEDT model reaches 0. 756. The IoU of HRMEDS model also reaches 0. 710 and params is only 3. 99 M.
Li et al. (Mon,) studied this question.
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