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Urinary Plasminogen as a Marker of Disease Progression in Human Glomerular Disease | Synapse

March 5, 2024Open Access

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Urinary Plasminogen as a Marker of Disease Progression in Human Glomerular Disease

MCMarina de CosIcahn School of Medicine at Mount Sinai GMGohar MosoyanIcahn School of Medicine at Mount Sinai KCKinsuk ChauhanThe Royal Melbourne Hospital

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Resumen

Glomerular disorders have a highly variable clinical course, and biomarkers that reflect the molecular mechanisms underlying their progression are needed. Based on our previous work identifying plasminogen as a direct cause of podocyte injury, we designed this study to test the association between urine plasmin(ogen) (ie, plasmin and its precursor plasminogen) and end-stage kidney disease (ESKD).

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Cite This Study

Cos et al. (Tue,) studied this question.

synapsesocial.com/papers/68e75a0cb6db6435876d15e4 https://doi.org/https://doi.org/10.1053/j.ajkd.2024.01.520