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Introduction/Background When endometrial carcinoma invades the cervix, the risk of recurrence increases. However, whether patients should be treated with extrafascial hysterectomy with pelvic lymphadenectomy or radical hysterectomy and pelvic lymphadenectomy is still controversial. Methodology This is a retrospective study on a total of 70 patients with endometrial carcinoma stage IIA FIGO (with cervical involvement). The study was conducted at 'Carol Davila' Central Military Emergency University Hospital, Romania between 2020–2023, and the patients were divided in two groups, according to the type of hysterectomy (extrafascial or radical). All the patients received pelvic lymphadenectomy. A pathologist evaluated all slides to determine the depth of cervical invasion. Demographics (i.e., age and family history of malignancy), depth of cervical involvement, and follow-up were collected. Results The mean age at diagnosis was 65,2 years. Only 48 (68.57%) patients had a family history of malignancy, without any statistical significance between groups. Fourteen patients (20%) were treated by extrafascial hysterectomy with pelvic lymphadenectomy and 56 (80%) by radical hysterectomy and pelvic lymphadenectomy. On pathologic examination, 52.85% (n=37) patients had less than half of the cervical stromal involvement, 21.42% (n=15) had half of the cervical stromal involvement and 25.71% (n=18) had more than half of the cervical stromal involvement, without any statistical significance. Only forty-two (60%) patients received adjuvant radiation. The mean follow-up period was 24 months. There were only 17 recurrences and 9 disease-related deaths in both groups. Conclusion Our study showed that neither extrafascial hysterectomy nor radical hysterectomy was associated with an increased risk of recurrence in endometrial carcinoma with cervical stromal involvement Disclosures Nothing to disclose.
Dalaty et al. (Fri,) studied this question.