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Abstract The global environmental issue of soil contamination with antibiotic-resistance genes has garnered increased attention in recent years due to its impact on ecosystems and human health. Despite this recognition, researchers face challenges in comprehensively understanding the mechanisms underlying the production and dissemination of soil resistance genes, particularly in relation to their implications for human health. This lack of understanding poses a barrier to the development of effective and precise control strategies. Biochar, a sustainable material, exhibits favorable adsorption properties characterized by its large pores and specific surface area. Therefore, we propose to explore the potential application of biochar addition in soil resistance gene management. In order to establish a solid research foundation in this area, in this paper we review the mechanisms underlying the generation and accumulation of soil resistance genes over the last decade, along with their transmission pathways and interfacial interactions. Biochar may help repair soil resistance genes by affecting factors like antibiotic levels, environmental conditions, enzymatic activity, and gene migration mechanisms, opening up new research possibilities. Graphical Abstract
Li et al. (Wed,) studied this question.
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