March 22, 2024Open Access

SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia

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Abstract

In a phenotypical screen of 56 acute myeloid leukemia (AML) patient samples and using a library of 10,000 compounds, we identified a hit with increased sensitivity toward

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Authors

Céline Moison

Deanne Gracias

Julie Schmitt

Journals

Science Advances

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Institutions

Université de Montréal

Bristol-Myers Squibb (United States)

Hôpital Maisonneuve-Rosemont

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SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia

Key Points

Abstract

Citation Network

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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