Abstract 6477: Modulators of hospital length of stay after intracranial neoplasm excision

Abstract Purpose: Intracranial neoplasms are the leading cause of cancer death among men under 40 years old. A major part of the standard of care is excision of the tumor, but there is a lack of robust large-patient studies of outcomes for these patients. Methods: The Nationwide Inpatient Sample was queried from 2018 to 2020 to identify patients with an intracranial neoplasm. Multivariable linear regression with patient- and hospital-level characteristics as covariates was used to identify factors associated with long hospital stays. Results: From 2018 to 2020, there were 97, 795 hospital encounters with a primary diagnosis of an intracranial neoplasm. Of these patients, 64. 6% underwent a tumor excision procedure during their hospital visit. The average age of these patients undergoing excision was 57. 80. 2 years. Most patients were male (58. 6%), white (79. 1%), private insurance beneficiaries (46. 3%), and of the highest income quartile (26. 8%). These patients most commonly presented to hospitals in the West (34. 9%), with a medium number of beds (36. 4%), and presented to rural hospitals (41. 7%). The most common locations of these neoplasms were the frontal (29. 1%), temporal (21. 3%), and parietal (12. 1%) lobes. Neoplasms in more than one location in the brain occurred in 4. 5% of patients. Multivariable linear regression identified the following factors as significantly associated with longer hospital stays: identifying as Black (beta=2. 08; p0. 001), identifying as an Asian or Pacific Islander (beta=1. 22; p=0. 017), being a Medicaid beneficiary (beta=2. 25; p0. 001), and being uninsured (beta=1. 63; p0. 001). Having a neoplasm in the cerebral ventricle (beta=4. 93; p0. 001), cerebellum (beta=2. 81; p0. 001), or brain stem (beta=3. 45; p0. 001), and having multiple neoplasms (beta=1. 85; p=0. 008) were also associated with longer hospital stays. Interestingly, having a parietal (beta=-0. 54; p=0. 011) or occipital (b=-0. 99; p0. 001) lobe neoplasm was associated with shorter hospital stays. Conclusion: Intracranial neoplasms are deadly condition and excision of tumor is a important life-saving treatment option. In this study, we demonstrated that location of neoplasm, race, and insurance status are significant modulators of the length of a hospital stay after surgery. Citation Format: Jayla Hsiung, Kamil Taneja, Lauren Ladehoff, Karan Patel, Eric Toloza. Modulators of hospital length of stay after intracranial neoplasm excision abstract. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts) ; 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84 (6Suppl): Abstract nr 6477.