Synthesis and Characterisation of Ag-Co-Venlafaxine-Cyclodextrin Nanorods

Ag and Ag/Co nanoparticles containing venlafaxine/cyclodextrin (VF/CD) inclusion complexes were synthesized and analyzed by UV-Visible, fluorescence, computational technique, DSC, FTIR, XRD, FE-SEM, and TEM. Single emission was observed in α-CD and β-CD. A blue-shifted absorption and fluorescence maximum was seen in Ag/VF/CD and Ag/Co/VF/CD nanoparticles than VF/CD inclusion complex. TEM image exposed the existence of nanorods in Ag/VF/β-CD and Ag/Co/VF/β-CD. Pure VF drug shows more antibacterial activity than Ag/VF/β-CD and Ag/Co/VF/β-CD nanomaterials. Nano particle size is also measured by X-RD and TEM.