Wcn24-2635 Drug-Induced Acute Kidney Injury: Cohort Study on Incidence, Identification of Pathophysiological Mechanisms and Prognostic Factors

Drug-Induced Acute Kidney Injury (DIAKI) can be classified in type A reactions, in which the mechanism of aggression is explained by the drug pharmacology (time of use and dose) and in type B reactions, when the nephrotoxicity can not be predictable and depends on drug pharmacogenetics and corresponds to Acute Interstitial Nephritis (AIN), crystalline nephropathy and tubular diseases (Bartterlike or Gitelman-like). This study aimed to determine the incidence of DIAKI, the associated drugs, its phenotypes and the main prognostic factors.