Evaluation of lipoproteins and high sensitivity crp in consumers of bakery products

Background.In recent years, a wider range of bakery products with a lower glycaemic response can be observed in the food industry.This contributes to the provision of a wider range of cereal bakery products.The gradual increase in the consumption of brown bread is significant, but despite this, white bread remains a part of the typical Western diet.Studies showed high intake of carbohydrates increase TG levels by enhancing hepatic synthesis of very low-density lipoprotein (VLDL) and decrease activity of lipoprotein lipase.White bread consumption has been therefore associated with an unhealthy lifestyle.Objective.The aim of this study was to assess the influence of the consumption of gluten bakery products on lipids and inflammatory parameters of the probands.Material and Methods.The monitored group consisted of 30 probands from the general population.The average age of the monitored group was 29.7 years.The intervention dose consisted of a different combination of several types of bakery products containing gluten (bread, pastries, soft pastries) within the individual weeks of consumption, while the intervention lasted 6 weeks.An intervention dose of 150 to 200 g per day was set for women and 200 to 250 g per day for men.Biochemical blood parameters were determined using a fully automatic Biolis 24i Premium blood serum biochemical analyzer, by end-point photometry method.We tested the differences between the biochemic parameters by one-factor analysis of variance (ANOVA) and compared them by Tuckey's Post Hoc Test.Results.The measurement of the lipid profile showed that the average levels of total cholesterol (TC) were above the reference value (<5.00 mmol.l-1) in each of the three performed measurements (P˂0.01).In the case of LDL, we found a similar trend in the development of lipoprotein values, while we positively evaluate a slight reduction of LDL in the measurement immediately after the intervention (P˂0.001).Certain changes during the study were also noted in HDL parameters with high statistical significance (P˂0.001).During the TG analysis, we found that probands have normal values (0.45-2.70 mmol.l-1).A reduction in average TG values was achieved in individual measurements, but without statistical significance (P˃0.05).In high sensitivity CRP (hs-CRP) parameters was achieved a bell curve of the development of average values, with a maximum measured immediately after the intervention.Changes in hs-CRP during the study were without statistical significance (P˃0.05)Conclusions.The measurement of the lipid profile showed that the average levels of TC, LDL and HDL, there were above the reference value in each of the three measurements performed.Through the analysis of TG, we found normal values and during the study there was a slight decrease.Furthermore, we found that intervention with bakery products containing gluten was associated with an increase in hs-CRP levels in our probands.