Does transcatheter aortic valve replacement improve left atrial mechanics and remodelling?
TAVR is associated with significant improvement in left atrial mechanics and negative remodeling, though prognostic implications require further study.
Aims: The morphology and function of the left atrium (LA) are intimately tied to left ventricular loading conditions. Data pertaining to the effect of transcatheter aortic valve replacement (TAVR) on LA function and geometry are scarce. The aim of the study was to quantify associations between TAVR and LA remodelling by pooling available data from published observational studies. Methods and results: < 0.01). Conclusion: TAVR is associated with significant negative LA remodelling, and an improvement in LA mechanics, quantified by STE. The prognostic implications of these findings require further study.
Meredith et al. (Mon,) studied this question.
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