Mp08-09 the Impact of Surgical Time and Clinical Characteristics on Thromboembolic Events Following Radical Cystectomy: Results of a Contemporary Cohort of Patients

You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation I (MP08)1 May 2024MP08-09 THE IMPACT OF SURGICAL TIME AND CLINICAL CHARACTERISTICS ON THROMBOEMBOLIC EVENTS FOLLOWING RADICAL CYSTECTOMY: RESULTS OF A CONTEMPORARY COHORT OF PATIENTS Ruben Blachman-Braun, Jessica Delgado, Pedro F.S. Freitas, Tarek Ajami, Aaron A. Gurayah, Mark L. Gonzalgo, Bruno Nahar, Sanoj Punnen, Dipen J. Parekh, and Chad R. Ritch Ruben Blachman-BraunRuben Blachman-Braun , Jessica DelgadoJessica Delgado , Pedro F.S. FreitasPedro F.S. Freitas , Tarek AjamiTarek Ajami , Aaron A. GurayahAaron A. Gurayah , Mark L. GonzalgoMark L. Gonzalgo , Bruno NaharBruno Nahar , Sanoj PunnenSanoj Punnen , Dipen J. ParekhDipen J. Parekh , and Chad R. RitchChad R. Ritch View All Author Informationhttps://doi.org/10.1097/01.JU.0001008780.87855.57.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patients undergoing radical cystectomy (RC) might experience postoperative complications, among those thromboembolic events have been associated with significant morbidity and mortality. Thus, this study aims to investigate the association between clinical, demographic, and surgical characteristics with thromboembolic events in a contemporary cohort of patients. METHODS: Using the National Surgical Quality Improvement Program surgical registry from 2015-2020, we selected patients ≥18 years that had the diagnosis of bladder cancer (ICD-10: C66, C65, C67, D09.0, or Z85.5, and ICD-9: 188,189, or 233.7) and underwent RC. Patients who underwent surgical procedures in which the urinary diversion method was not recorded were excluded. Thromboembolic events (pulmonary embolism or deep vein thrombosis) within the 30-day postoperative period were recorded. A multivariable-adjusted logistic regression was performed to identify the clinical variables associated with thromboembolic events. SPSS 28 was used for statistical analysis. RESULTS: A total of 12,246 patients were analyzed, consisting of 10,308 (84.2%) who underwent RC with incontinent urinary diversion and 1,938 (15.8%) continent urinary diversion. The mean age was 69.1±9.6 years, BMI 28.5±5.7 kg/m2, 10,055 (82.1%) were males, 8,955 (73.1%) were white, 2,748 (22.4%) were current smokers, and 7,332 (59.9%) had hypertension. Overall median surgical time was 5.3 4.1-6.8 hours. There were 407 patients with thromboembolic events (382 thromboembolic events and 25 combined with another major adverse cardiovascular event). Increased age, obesity, RC with continent urinary diversion, and increase surgical time were associated with an increased risk of thromboembolic events (Table 1). CONCLUSIONS: Patients with obesity, older patients, those who underwent RC with a continent urinary diversion approach, and those with increased operative time have a higher risk of developing postoperative thromboembolic events. Our findings can assist urologists with preoperative counseling and ensuring medical optimization for patients at risk. Urologists should aim for lower operative times. Source of Funding: No © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e117 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Ruben Blachman-Braun More articles by this author Jessica Delgado More articles by this author Pedro F.S. Freitas More articles by this author Tarek Ajami More articles by this author Aaron A. Gurayah More articles by this author Mark L. Gonzalgo More articles by this author Bruno Nahar More articles by this author Sanoj Punnen More articles by this author Dipen J. Parekh More articles by this author Chad R. Ritch More articles by this author Expand All Advertisement PDF downloadLoading ...