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You have accessJournal of UrologyPenile p=0.009). However, the receipt of radiation did not significantly differ across T stages. Kaplan-Meier survival analysis revealed no survival benefit associated with either chemotherapy or radiation. Contrarily, lymph node dissection was significantly associated with disease-specific survival benefits in the overall cohort (p<0.001), T2 stage (p=0.040), and T3 stage (p=0.002). Multivariable Cox analysis further underscored lymph node dissection as an independent protective prognostic factor (HR=0.483, 95% CI 0.328–0.711, p<0.001). CONCLUSIONS: Our analysis suggests a possible survival benefit from regional lymph node dissection in lymph node-negative penile squamous cell carcinoma patients. However, these results, derived from retrospective data, should be interpreted with caution. It is clear that more research is needed. Specifically, well-designed prospective studies are essential to further explore and validate the potential benefits of lymph node dissection in this patient population. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1013 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Hangcheng Fu More articles by this author Murali Ankem More articles by this author Expand All Advertisement PDF downloadLoading ...
Fu et al. (Mon,) studied this question.