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You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology IV (MP62)1 May 2024MP62-15 METABOLIC SYNDROME IS ASSOCIATED WITH POSTOPERATIVE COMPLICATIONS AFTER HOLEP Victoria S. Edmonds, Daniel Heidenberg, and Mitchell R. Humphreys Victoria S. EdmondsVictoria S. Edmonds , Daniel HeidenbergDaniel Heidenberg , and Mitchell R. HumphreysMitchell R. Humphreys View All Author Informationhttps://doi.org/10.1097/01.JU.0001008904.63948.3b.15AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Metabolic syndrome (MetS) has been shown to be independent risk factors for postoperative infections, cardiac and pulmonary complications, prolonged hospitalizations, and reoperation. However, the impact of MetS on postoperative complications after Holmium Enucleation of the Prostate (HoLEP) has not been well described. We sought to evaluate the relationship between MetS and postoperative complications after HoLEP. METHODS: We performed a retrospective review of all patients who underwent HoLEP at a single institution from 2007 to 2019. Patient demographics, comorbidities, and postoperative complications were collected. Diagnostic criteria for MetS was assumed to be met with at least 3 of 4 preoperative diagnoses of diabetes mellitus (DM), hypertension (HTN), hyperlipidemia (HLD), or BMI>35. Continuous variables were compared using Student T-tests. A Chi-square tests of independence was performed to determine the relationship between MetS and postoperative complications, both during the same hospitalization (immediate) and after discharge but within 30 days (late). RESULTS: A total of 2017 patients underwent HoLEP at our institution between 2007 and 2019 with mean age 78 (SD 9.3). Of these, 230 (11.4%) met criteria for MetS and 1787 (88.6%) did not (Table 1). There were 114 immediate complications and 185 late complications. The most common complication immediately after surgery was bleeding (n=44), while the most common complication within 30 days was urinary incontinence (n=22). There was an association between MetS and a complication during the same hospitalization and within 30 days (p<0.001). CONCLUSIONS: A preoperative diagnosis of MetS was significantly associated with postoperative complications, both within the same hospitalization and after discharge but within 30 days. This suggests that the cluster of biochemical and physiologic changes that define MetS have an influence on postoperative recovery after HoLEP, which could be an important factor to consider in preoperative counseling and patient selection. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1027 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Victoria S. Edmonds More articles by this author Daniel Heidenberg More articles by this author Mitchell R. Humphreys More articles by this author Expand All Advertisement PDF downloadLoading ...
Edmonds et al. (Mon,) studied this question.