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You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction (Excluding OAB) (MP75)1 May 2024MP75-14 DOES SEVERITY OF CHRONIC URINARY RETENTION NEGATIVELY IMPACT THE OUTCOME OF HOLMIUM LASER ENUCLEATION OF PROSTATE? Diana M. Lopategui, Ruben Blachman-Braun, Joao G. Porto, Mohamadhusni Zarli, Theodora M. Zavos, Ryan Chen, Robert Marcovich, and Hemendra N. Shah Diana M. LopateguiDiana M. Lopategui , Ruben Blachman-BraunRuben Blachman-Braun , Joao G. PortoJoao G. Porto , Mohamadhusni ZarliMohamadhusni Zarli , Theodora M. ZavosTheodora M. Zavos , Ryan ChenRyan Chen , Robert MarcovichRobert Marcovich , and Hemendra N. ShahHemendra N. Shah View All Author Informationhttps://doi.org/10.1097/01.JU.0001008676.21744.5f.14AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Long term bladder obstruction can impair bladder contractility, which has been linked to failure to improve lower urinary tract symptoms after bladder outlet procedures. Elevated post—void residual (PVR) constitutes a proxy for chronic retention and detrusor underactivity that can be non-invasively determined in office. We examined the outcomes of a prospective cohort of men undergoing Holmium Laser Enucleation of Prostate (HoLEP) based on their pre-operative PVR, to assess its influence on surgical outcomes. METHODS: We evaluated men undergoing HoLEP from July 2017 to August 2022 from our prospectively maintained institutional database. Patients with acute urinary retention and those lacking baseline PVR values were excluded. Patients underwent "en-bloc" HoLEP. Follow up protocol included PVR, PSA, International Prostate Symptom Score (IPSS) and uroflowmetry before surgery; and at 3 months, 6 months and 1 year post-operatively. Clinical characteristics and post-operative outcomes were compared between patients with pre-operative PVR600. Statistical analysis was performed with SPSS version 28 software. RESULTS: We included 318 men in the analysis and found no significant differences between the groups regarding clinical characteristics, as well as perioperative details including operative time, resected volume, catheter time and complications (Table 1). Post-operative improvement in voiding parameters was found to be similar in all four groups of study up to one year of follow up (Table 2). CONCLUSIONS: Severity of chronic urinary retention does not impact the outcomes of HoLEP. Our data should assist in reassuring patients with large bladder capacity that HoLEP can provide them with excellent functional voiding outcomes. provided great improvement in voiding parameters to men with lower urinary tract symptoms secondary to benign prostatic hyperplasia, with no significant differences in outcomes between patient with preoperative PVR600 cc. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1237 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Diana M. Lopategui More articles by this author Ruben Blachman-Braun More articles by this author Joao G. Porto More articles by this author Mohamadhusni Zarli More articles by this author Theodora M. Zavos More articles by this author Ryan Chen More articles by this author Robert Marcovich More articles by this author Hemendra N. Shah More articles by this author Expand All Advertisement PDF downloadLoading ...
Lopategui et al. (Mon,) studied this question.