Pd33-10 Robot-Assisted Partial Nephrectomy With Hugo™ Ras System: Perioperative Outcomes and Trifecta Achievement From the Largest Multicentric Series

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy II (PD33)1 May 2024PD33-10 ROBOT-ASSISTED PARTIAL NEPHRECTOMY WITH HUGO™ RAS SYSTEM: PERIOPERATIVE OUTCOMES AND TRIFECTA ACHIEVEMENT FROM THE LARGEST MULTICENTRIC SERIES Francesco Prata, Paolo Dell'Oglio, Francesco Chierigo, Angelo Mottaran, Chiara Sighinolfi, Angelo Civitella, Andrea Iannuzzi, Pietro Piazza, Matteo Pira, Alberto Ragusa, Francesco Tedesco, Riccardo Schiavina, Bernardo Rocco, Eugenio Brunocilla, Antonio Galfano, Roberto Mario Scarpa, and Rocco Papalia Francesco PrataFrancesco Prata , Paolo Dell'OglioPaolo Dell'Oglio , Francesco ChierigoFrancesco Chierigo , Angelo MottaranAngelo Mottaran , Chiara SighinolfiChiara Sighinolfi , Angelo CivitellaAngelo Civitella , Andrea IannuzziAndrea Iannuzzi , Pietro PiazzaPietro Piazza , Matteo PiraMatteo Pira , Alberto RagusaAlberto Ragusa , Francesco TedescoFrancesco Tedesco , Riccardo SchiavinaRiccardo Schiavina , Bernardo RoccoBernardo Rocco , Eugenio BrunocillaEugenio Brunocilla , Antonio GalfanoAntonio Galfano , Roberto Mario ScarpaRoberto Mario Scarpa , and Rocco PapaliaRocco Papalia View All Author Informationhttps://doi.org/10.1097/01.JU.0001008912.25331.d7.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Robot Assisted Partial Nephrectomy (RAPN) is widely performed in tertiary referral urological centers. We aimed to describe perioperative outcomes of the largest multicentric series of RAPNs performed with the new HugoTM RAS System. METHODS: Four prospectively maintained dataset from tertiary referral centers were merged and queried for "RAPN" and "Hugo", performed since October 2022. A total of 52 patients were enrolled. Baseline and perioperative data were collected. Trifecta was defined as the coexistence of: negative surgical margin status, no Clavien-Dindo grade ≥3 complications, eGFR decline ≤30%. In case of on-clamp procedure, a warm ischemia time (WIT) <25 min was considered mandatory for trifecta achievement. A two-sided p-value <0.05 was considered statistically significant. RESULTS: All patients successfully underwent RAPN without the need of conversion to open surgery or additional port placement. Median age and BMI were 64 years (56-72) and 26 kg (24.2-27.7), respectively (Table 1). Median clinical tumor size was 27 mm (17-38.5). Most patients (40.4%) presented with left renal mass and 8 (1.5%) patients had cystic features at preoperative imaging. Regarding postoperative data (Table 2), median docking time and console time were 5 min (4-6) and 145 min (75-200), respectively. Median estimated blood loss was 100 ml (250-300). With respect to postoperative complications, four patients displayed Clavien-Dindo II (single-unit blood transfusion or fever) while four patients experienced Clavien-Dindo IIIa (one lymphocele, two pneumothorax and one pseudoaneurysm). At discharge, median serum creatinine and eGFR were 0.95 mg/dl (0.82-1.16) and 72.1 ml/min/1.73 m2 (61.3-89.7) were comparable to preoperative values. At final histopathological report, most patients (57.7%) presented with Clear cell RCC while only 2 (3.9%) had positive surgical margins. Overall, Trifecta was achieved in 47 (90.4%) of patients. CONCLUSIONS: This study represents the initial multicentric series demonstrating the application of Hugo™ RAS system in the context of RAPN. The promising outcomes and cost-effectiveness may lead urologists to use Hugo Ras system in the nephron-sparing surgical landscape. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e714 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Francesco Prata More articles by this author Paolo Dell'Oglio More articles by this author Francesco Chierigo More articles by this author Angelo Mottaran More articles by this author Chiara Sighinolfi More articles by this author Angelo Civitella More articles by this author Andrea Iannuzzi More articles by this author Pietro Piazza More articles by this author Matteo Pira More articles by this author Alberto Ragusa More articles by this author Francesco Tedesco More articles by this author Riccardo Schiavina More articles by this author Bernardo Rocco More articles by this author Eugenio Brunocilla More articles by this author Antonio Galfano More articles by this author Roberto Mario Scarpa More articles by this author Rocco Papalia More articles by this author Expand All Advertisement PDF downloadLoading ...