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You have accessJournal of UrologyHealth Services Research: Practice Patterns, Quality of Life and Shared Decision Making I (MP12)1 May 2024MP12-02 FINANCIAL TOXICITY AND QUALITY OF LIFE POST CHEMOTHERAPY FOR TESTICULAR GERM CELL TUMORS Shaun Trecarten, Anand Iyer, Mukund Bhandari, Chethan Ramamurthy, and Deepak Pruthi Shaun TrecartenShaun Trecarten , Anand IyerAnand Iyer , Mukund BhandariMukund Bhandari , Chethan RamamurthyChethan Ramamurthy , and Deepak PruthiDeepak Pruthi View All Author Informationhttps://doi.org/10.1097/01.JU.0001009376.16371.fb.02AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Financial toxicity (FT) is the direct/indirect health care cost that burdens patients and their family, often leading to poorer quality of life. For men with metastatic testicular germ cell tumors (mtGCT), chemotherapy can have long term physical and mental health consequences, increasing the risk for FT, which has been largely understudied. The purpose of this study is to evaluate and identify risk factors for FT in mtGCT patients post chemotherapy. METHODS: Patients with mtGCT were included if at least>2 cycles of chemotherapy were completed within the last 1-5 years. Between 11/2022 and 10/2023, eligible patients completed the COmprehensive Score for financial Toxicity (COST), EORTC QLQ-C30, and EORTC QLQ-TC26 questionnaires. Demographic and disease-specific data was also collected. Descriptive statistics were used to summarize responses. Wilcoxon-Rank Sum Test was used to evaluate differences in survey responses between selected groups. RESULTS: Respondents (N=25, response rate=56.8%) reported a median age of 29 years (IQR 25-33) and 84% (n=21) identified as white-Hispanic. Eight (32%) patients were unemployed and 5(20%) and 3(12%) patients were uninsured or on Carelink respectively. Having insufficient funds/savings to cover treatment costs was reported in 48%(n=12) patients. All patients felt financially stressed, with 44% (n=11) feeling at least 'quite a bit'. A response of at least 'quite a bit' was reported in 60%(n=15) patients for a reduction in financial satisfaction due to the cancer/treatment, and in 52% (n=13) for the illness being a financial hardship (FH). Those without insurance/on Carelink reported higher median scores for the illness being a FH (4 Very much vs 2Somewhat, p=0.047). Unemployed patients reported higher median scores for financial stress (3 Quite a bit vs 2, p=0.005) and frustration at not working/contributing as much as usual (3 Quite a bit vs 1.5, p=0.048). Peripheral neuropathy was associated with reduced median quality of life scores (5.5 vs 7 max 7, p=0.01) and increased median scores for having physical limitation as a result of the disease/treatment (2 A little vs 1Not at all, p=0.01). CONCLUSIONS: Patients post chemotherapy for mtGCT (especially those without insurance/employment) suffer from FT. Efforts to support these young men should be promoted. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e200 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Shaun Trecarten More articles by this author Anand Iyer More articles by this author Mukund Bhandari More articles by this author Chethan Ramamurthy More articles by this author Deepak Pruthi More articles by this author Expand All Advertisement PDF downloadLoading ...
Trecarten et al. (Mon,) studied this question.