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As a producer of industrial enzymes and secondary metabolites, Bacillus subtilis is generally considered to be more beneficial for humans, animals, and notably industry. Consequently, it is imperative to investigate various Bacillus spp at the genome level. The comparative genomics of Bacillus spp is the subject of this manuscript. Wherein various Bacillus spp genomes were collected and examined. The sources of the bacteria included fermented foods, soil, and liquid wastes. A wide range of bioinformatics resources and tools were used in the study for genome annotation, assembly, and comparison. The isolate B. subtilis S2 is closely linked to the B. subtilis SRCM103571 and B. subtilis SRCM104005 species cluster, according to the phylogenetic tree analysis. The WGS is also unique in that it produces two bacteriocins, Sublancin and Subtilosin A, according to antiSMASH & BAGEL-4 analysis. Subsequent investigation revealed that it has the fewest rRNA -just nine-and tRNA -72. However, at 4438, it has the highest number of genes, which makes the S2 strain distinct at the genome level. We conclude by noting the different nature of B. subtilis S2.
Jain et al. (Fri,) studied this question.