Mp75-17 Examining the Relationship Between Dietary Inflammatory Index and Urinary Flow Rate: Results From a Nationwide Study

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction (Excluding OAB) (MP75)1 May 2024MP75-17 EXAMINING THE RELATIONSHIP BETWEEN DIETARY INFLAMMATORY INDEX AND URINARY FLOW RATE: RESULTS FROM A NATIONWIDE STUDY Yifan Li and Lu Yang Yifan LiYifan Li and Lu YangLu Yang View All Author Informationhttps://doi.org/10.1097/01.JU.0001008676.21744.5f.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: While existing evidence indicates that different nutrients and inflammatory markers may impact urinary function, the relationship between diet and urinary flow rate (UFR) remains uncertain. Therefore, our primary objective is to assess the connection between the dietary inflammatory index (DII) and UFR. METHODS: We conducted a cross-sectional analysis utilizing data gathered from the Continuous National Health and Nutrition Examination Survey (NHANES) spanning the years 2009 to 2016. Our study's primary variables were UFR as the dependent variable and DII score as the independent variable. We collected dietary information through 24-hour dietary recall surveys, from which we computed DII scores. We categorized participants into tertiles based on their DII scores. Our analysis also incorporated demographic information, comorbidities, dietary data, and physical examination data as covariates. RESULTS: The study encompassed 17,114 NHANES participants with available data on both DII and UFR. The average age of these participants was 35.68 years (±20.96). Among the participants, 62.87% identified as non-Hispanic white, 11.65% as non-Hispanic black, and 6.4% as of Hispanic heritage. Notably, individuals with higher DII scores exhibited a corresponding decrease in UFR levels (β= -0.03; 95% CI: -0.04–-0.01). Moreover, there was a significant and progressive increase in the risk of UFR decline observed across the tertiles of DII scores (p for trend <0.001). CONCLUSIONS: Our results indicate that a greater consumption of a pro-inflammatory diet, as indicated by higher DII scores, is associated with a reduction in urinary flow rate. These findings have implications for public health interventions aimed at offering primary prevention advice for lower urinary tract voiding issues. However, it is essential to note that further rigorous prospective research is required to confirm and expand upon these observations. Source of Funding: This program was supported by the National Natural Science Foundation of China (Grant Nos. 81974099, 82170785, 81974098, 82170784), programs from Science and Technology Department of Sichuan Province (Grant Nos. 21GJHZ0246), Young Investigator Award of Sichuan University 2017 (Grant No. 2017SCU04A17), Technology Innovation Research and Development Project of Chengdu Science and Technology Bureau (2019-YF05-00296-SN), Sichuan University--Panzhihua science and technology cooperation special fund (2020CDPZH-4) © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1239 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Yifan Li More articles by this author Lu Yang More articles by this author Expand All Advertisement PDF downloadLoading ...