Adenoid cystic carcinoma of the male breast: Case report and review of literature

Male synchronous bilateral breast cancer of Adenoid cystic carcinomaACC) is extremely rare. : A 84-year-old male presented with a simultaneously, bilateral, rapidly growing lump in breast of three months duration. Physical examination right breast, revealed a single subareolar mass measuring 3.4 x 3 x2.8 cm. It was firm to hard, well-defined mass with retraction of nipple. The left breast mass was firm tender, measuring 3.1x2.5x2.1cm with irregular margins. Bilateral lymphadenopathy was noted. Sonommamography was suspicious of neoplastic lesion with secondary changes. The FNAC reported as positive for carcinoma cell of bilateral breasts. The bilateral modified radical mastectomy was done. On histopathology, we reported as bilateral breast cancer of Adenoid cystic carcinomasolid, cribriform, tubular pattern, grade III in right breast and ACC with areas of invasive breast carcinoma and neuroendocrine features in left breast. All 24 right and left axillary lymph nodes were negative for metastesis. On immunohistochemistry staining tumor cells were negative for Estrogen Receptor, progesterone receptor, HER2/neu oncogene. ACC of breast is a rare subtype of breast cancer. We present extremely rare case of male synchronous bilateral breast cancer of ACC for its clinical manifestations, radio imaging, and histopathological features.