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Ebola virus disease (Ebola) is a rare but severe illness in humans, with an average case fatality rate of approximately 50%.Two licensed vaccines are currently available against Orthoebolavirus zairense, the virus that causes Ebola: the 1-dose rVSVΔG-ZEBOV-GP (ERVEBO Merck) and the 2-dose regimen of Ad26.ZEBOV and MVA-BN-Filo (Zabdeno/ Mvabea [Johnson 95%) shipped from the ICG stockpile have been repurposed for preventive vaccination of high-risk groups, compared with 6,570 (5%) used for outbreak response.Repurposing doses for preventive vaccination could be prioritized in the absence of Ebola outbreaks to prevent transmission and maximize the cost-efficiency and benefits of the stockpile.
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Ruth Kallay
Centers for Disease Control and Prevention
Reena H. Doshi
Centers for Disease Control and Prevention
Pierre Muhoza
Centers for Disease Control and Prevention
MMWR Morbidity and Mortality Weekly Report
AID Atlanta
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Kallay et al. (Thu,) studied this question.
synapsesocial.com/papers/68e6d7feb6db643587655447 — DOI: https://doi.org/10.15585/mmwr.mm7316a1