Key points are not available for this paper at this time.
Supplementary Figure S1. Analytical workflow for the C-CAT, GENIE, and TCGA cohorts.Supplementary Figure S2. Comparison of targeted gene panels.Supplementary Figure S3. Comparison of genetic alterations in C-CAT and GENIE cohorts.Supplementary Figure S4. Comparison of mutation frequency, type, and position in C-CAT and GENIE cohorts.Supplementary Figure S5. Co-occurring and mutually exclusive relationships across cohorts.Supplementary Figure S6. Co-occurring and mutually exclusive relationships across cancer types/subtypes.Supplementary Figure S7. Co-occurring and mutually exclusive relationships using a permutation approach.Supplementary Figure S8. Co-occurring and mutually exclusive relationships across driver mutations in epigenetic regulators.Supplementary Figure S9. Functional and prognostic relevance of driver mutations in epigenetic regulators.
Horie et al. (Wed,) studied this question.