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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare genetic disorder caused by mutations in the NOTCH3 gene, resulting in subcortical infarctions and leukoencephalopathy. It predominantly affects the brain's small blood arteries, resulting in repeated ischemic episodes including transient ischemic attacks and strokes leading to cognitive impairment and mental symptoms. We provide a case study of a 25-year-old patient suspected of having meningoencephalitis. CADASIL was diagnosed based on clinical examination, imaging investigations, and genetic analysis. Optimal patient care for this complicated illness requires early detection and proper management.
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Zahid Ullah
Khyber Teaching Hospital
Ebad-Ur Rehman Syed
Royal College of Surgeons in Ireland
Noman Salih
Medical University of Lublin
Cureus
Royal College of Surgeons in Ireland
Khyber Teaching Hospital
Hayatabad Medical Complex
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Ullah et al. (Thu,) studied this question.
synapsesocial.com/papers/68e6bea5b6db64358763ec38 — DOI: https://doi.org/10.7759/cureus.59550