Lower Urinary Tract Symptoms in US Women: Contemporary Prevalence Estimates from the RISE FOR HEALTH Study

You have accessJournal of UrologyAdult Urology4 May 2024Lower Urinary Tract Symptoms in US Women: Contemporary Prevalence Estimates from the RISE FOR HEALTH Study Siobhan Sutcliffe, Chloe Falke, Cynthia S. Fok, James W. Griffith, Bernard L. Harlow, Kimberly A. Kenton, Cora E. Lewis, Lisa Kane Low, Jerry L. Lowder, Emily S. Lukacz, Alayne D. Markland, Gerald McGwin, Melanie R. Meister, Elizabeth R. Mueller, Diane K. Newman, Ratna Pakpahan, Leslie M. Rickey, Todd Rockwood, Melissa A. Simon, Abigail R. Smith, Kyle D. Rudser, and Ariana L. Smith Siobhan SutcliffeSiobhan Sutcliffe Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). https://orcid.org/0000-0002-4613-8107 , Chloe FalkeChloe Falke , Cynthia S. FokCynthia S. Fok , James W. GriffithJames W. Griffith , Bernard L. HarlowBernard L. Harlow , Kimberly A. KentonKimberly A. Kenton , Cora E. LewisCora E. Lewis , Lisa Kane LowLisa Kane Low , Jerry L. LowderJerry L. Lowder , Emily S. LukaczEmily S. Lukacz , Alayne D. MarklandAlayne D. Markland , Gerald McGwinGerald McGwin , Melanie R. MeisterMelanie R. Meister , Elizabeth R. MuellerElizabeth R. Mueller , Diane K. NewmanDiane K. Newman , Ratna PakpahanRatna Pakpahan , Leslie M. RickeyLeslie M. Rickey , Todd RockwoodTodd Rockwood , Melissa A. SimonMelissa A. Simon , Abigail R. SmithAbigail R. Smith Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). , Kyle D. RudserKyle D. Rudser , and Ariana L. SmithAriana L. Smith Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). for the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium View All Author Informationhttps://doi.org/10.1097/JU.0000000000004009AboutPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookLinked InTwitterEmail Abstract Background: To estimate the prevalence of a wide range of lower urinary tract symptoms (LUTS) in US women, and to explore associations with bother and discussion with healthcare providers, friends, and family. Materials and Methods: We analyzed baseline data collected from 5/2022-12/2023 in the RISE FOR HEALTH study—a large, regionally-representative cohort study of adult female community members. LUTS and related bother were measured by the 10-item Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index and discussion was assessed by a study-specific item. Results: Of the 3000 eligible participants, 73% (95% confidence interval CI = 71-74%) reported any storage symptoms, 52% (95% CI = 50-53) any voiding or emptying symptoms, and 11% (95% CI = 10-13%) any pain with bladder filling, for an overall LUTS prevalence of 79% (95% CI = 78-81%). This prevalence estimate included 43% (95% CI = 41-45%) of participants with mild-to-moderate symptoms and 37% (95% CI = 35-38%) with moderate-to-severe symptoms. Over one-third of participants reported LUTS-related bother (38%, 95% CI = 36-39%) and discussion (38%, 95% CI = 36-40%), whereas only 7.1% (95% CI = 6.2-8.1%) reported treatment. Urgency and incontinence (including urgency and stress incontinence) were associated with the greatest likelihood of bother and/or discussion (adjusted prevalence ratios = 1.3-2.3), even at mild-to-moderate levels. They were also the most commonly treated LUTS. Conclusions: LUTS, particularly storage LUTS such as urgency and incontinence, were common and bothersome in the RISE study population, yet often untreated. Given this large burden, both prevention and treatment-related interventions are warranted to reduce the high prevalence and bother of LUTS. © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Supplementary Materials Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Siobhan Sutcliffe Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). More articles by this author Chloe Falke More articles by this author Cynthia S. Fok More articles by this author James W. Griffith More articles by this author Bernard L. Harlow More articles by this author Kimberly A. Kenton More articles by this author Cora E. Lewis More articles by this author Lisa Kane Low More articles by this author Jerry L. Lowder More articles by this author Emily S. Lukacz More articles by this author Alayne D. Markland More articles by this author Gerald McGwin More articles by this author Melanie R. Meister More articles by this author Elizabeth R. Mueller More articles by this author Diane K. Newman More articles by this author Ratna Pakpahan More articles by this author Leslie M. Rickey More articles by this author Todd Rockwood More articles by this author Melissa A. Simon More articles by this author Abigail R. Smith Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). More articles by this author Kyle D. Rudser More articles by this author Ariana L. Smith Corresponding Author: Siobhan Sutcliffe, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO ( (email protected) ) Ariana L. Smith, Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA ( (email protected) ). More articles by this author Expand All Advertisement PDF downloadLoading ...